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[1]
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SEQUENCE FROM NUCLEIC ACID.
MEDLINE=94099888; PubMed=8274221; [NCBI, ExPASy, EBI, Israel, Japan]
Cabeza-Arvelaiz Y.,
Shih L.-C.N.,
Hardman N.,
Asselbergs F.,
Bilbe G.,
Schmitz A.,
White B.,
Siciliano M.J.,
Lachman L.B.;
"Cloning and genetic characterization of the human kinesin light-chain (KLC) gene.";
DNA Cell Biol. 12:881-892(1993).
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[2]
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SEQUENCE FROM NUCLEIC ACID.
Gerber S.,
Rozet J.M.,
Perrault I.,
Ducroq D.,
Souied E.,
Munnich A.,
Kaplan J.;
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
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- FUNCTION: KINESIN IS A MICROTUBULE-ASSOCIATED FORCE-PRODUCING PROTEIN THAT MAY PLAY A ROLE IN ORGANELLE TRANSPORT. THE LIGHT CHAIN MAY FUNCTION IN COUPLING OF CARGO TO THE HEAVY CHAIN OR IN THE MODULATION OF ITS ATPASE ACTIVITY.
- SUBUNIT: OLIGOMERIC COMPLEX COMPOSED OF TWO HEAVY CHAINS AND TWO LIGHT CHAINS.
- TISSUE SPECIFICITY: FOUND IN A VARIETY OF TISSUES. MOSTLY ABUNDANT IN BRAIN AND SPINE.
- SIMILARITY: BELONGS TO THE KINESIN LIGHT CHAIN FAMILY.
- SIMILARITY: Contains 6 TPR repeats.
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This SWISS-PROT entry is copyright. It is produced through a collaboration
between the Swiss Institute of Bioinformatics and the EMBL outstation -
the European Bioinformatics Institute. There are no restrictions on its
use by non-profit institutions as long as its content is in no way
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entities requires a license agreement (See http://www.isb-sib.ch/announce/
or send an email to license@isb-sib.ch).
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10 20 30 40 50 60
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MSTMVYIKED KLEKLTQDEI ISKTKQVIQG LEALKNEHNS ILQSLLETLK CLKKDDESNL
70 80 90 100 110 120
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VEEKSNMIRK SLEMLELGLS EAQVMMALSN HLNAVESEKQ KLRAQVRRLC QENQWLRDEL
130 140 150 160 170 180
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ANTQQKLQKS EQSVAQLEEE KKHLEFMNQL KKYDDDISPS EDKDTDSTKE PLDDLFPNDE
190 200 210 220 230 240
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DDPGQGIQQQ HSSAAAAAQQ GGYEIPARLR TLHNLVIQYA SQGRYEVAVP LCKQALEDLE
250 260 270 280 290 300
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KTSGHDHPDV ATMLNILALV YRDQNKYKDA ANLLNDALAI REKTLGKDHP AVAATLNNLA
310 320 330 340 350 360
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VLYGKRGKYK EAEPLCKRAL EIREKVLGKD HPDVAKQLNN LALLCQNQGK YEEVEYYYQR
370 380 390 400 410 420
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ALEIYQTKLG PDDPNVAKTK NNLASCYLKQ GKFKQAETLY KEILTRAHER EFGSVDDENK
430 440 450 460 470 480
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PIWMHAEERE ECKGKQKDGT SFGEYGGWYK ACKVDSPTVT TTLKNLGALY RRQGKFEAAE
490 500 510 520 530 540
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TLEEAAMRSR KQGLDNVHKQ RVAEVLNDPE NMEKRRSRES LNVDVVKYES GPDGGEEVSM
550 560
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SVEWNGGVSG RASFCGKRQQ QQWPGRRHR
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Q07866 in FASTA format |
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