Gene annotation of genomes

ABSTRACT

Gene prediction based on sequence homology can be done with diffent types of sequences. From the RNA/DNA side databases store mRNAs, cDNAs and ESTs. Protein sequences are also very useful.
The central dogma

mRNA/cDNA

ESTs
Expressed Sequence Tags (ESTs) are partial cDNA sequences sequenced either from 5' or 3'.
Proteins

>Protein MPPCRNRDBBQQQQZILLLLMFPPSSWWWVVV RNRDCPPCGVYLLQQQQAAARRRCCFPPSSHK