SECISaln will predict a SECIS element in the query sequence, split it into its constituent parts and align these against a precompiled database of eukaryotic SECIS elements. The user can choose whether the database sequences are sorted by protein family or by species, thereby offering the possibility of comparing the submitted sequence to other, known SECISes. In addition, SECISaln returns a graphical image of the predicted structure of the user-submitted sequence as well as a multiple structural alignment of all SECIS elements of that type already present in the database.