Input the promoter sequences or the TF-maps to perform the multiple TF-map alignment
(please click here for further information about the data and the algorithm):

SEQUENCES/MAPS
>M13483 NNNNNNNNNNNNNNNTGGAAGATGAGAAGCCGCTGTTGCTCCCCTGCCGCCCTGGCCCAG CTGTCAGGACCCCTCAGCAGAGGGCAGGGCGCCAAGCCTTCCCACTGCATGTGGCTTATT GTCCCCAAGGCTGGCAGGGCTGCGGAGGACCGAATCCACAGACCATCCAGGGAGCACCCA CACCCCAGAAAGGGGGAGGGGTGGGCTGGCGTCACTTAGTCTTCCCCTGCCCCCTACCCT TCAGCGCCTGCCCCTCCCCAGCTCCCTATTTGGCCATCCCCCTGACTGCCCCCTCCCCTT CCTTACATGGTCTGGGGGCTCCCTGGCTGATCCTCTCCCCTGCCCTTGGCTCCATGAATG GCCTCGGCAGTCCTAGCGGGTGCGAAGGGGACCAAATAAGGCAAGGTGGCAGACCGGGCC CCCCACCCCTGCCCCCGGCTGCTCCAACTGACCCTGTCCATCAGCGTTCTATAAAGCGGC CCTCCTGGAGCCAGCCACCC >M26773 TGTCTGTCCCCTGCAGCCCCAGCCCAGCTGTCAGGACCCTTCTCCAAGGGCAGGGCGCCAAGTCTTCCGG CATTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGACTCATTGTCCCTTAGTTT GGAAGGGCTGAAGAGCAATAAGCCCACTCCACAACTAGGGAGCTCCCCCACCCAAGGGGCGCATTGGCAT CACATAGCCTTTCCCCGTCCCCCACCCCTTGCTGGCCTGCCCCTCCCTAGCTCCCTATATGGCCATTGCT CTGACTGCCCCCTCCCCTTCCTTACATGGTCTGGGAGCCCCCTGGCTGATCCTCTACCCTGCCCTTGGCT CCAAGAATGGCCTCAGCGGTCCTAGATGGTGCTAAGGCGACCAAATAAGGCAAGGTGGCAGATCAGGGGC CCCCCACCCCTGCCCCCGGCTGCTCCAACTGACCCCGTCCATCAGAGAGCTATAAAGCTGCGCTCCAGGC GACTGACACCC >galGal2_refGene_NM_001031229 TTAGCTGGTTTGAAATGATGATGGAGCACATACTATGGACAGTTTCAAAA CACATGCTGTCCTTGATTGCATTTTAAAGTCAGGATATCATCTTTCTACG TGCACCAGTCTTGTCAGGATGATAGAGGCAGGGGACATCATACTGAATCT GATGCAAAAAGACCTTTGTTTTTGCAGCTGTCAGTCCAGCAGTCTTCTTT ATCTCCCACCTACGCCTCAGTGGTGGATTTCCGTGGCCAAATTTAGATAA ACATTCGCTGTCTCAAAGCTGTGATGATCTGTCTTTCCATGCAGCAGGAC TGGAATAGTTCCATGGAGTACTTTGAATTATGTCTGGTGCATACAGCCTT CCTGCCTATCAGTTCCTTTTATACCGCATTCTCTGTCTTACAGGGTGGTT CTGGTACCTCACTTTGTTTTTTTTTTTTCAATTATTCTTTTCTTGCTGTT TTCATAGGGCTGTTTTCTGCTTGGAGCACCTGAGGACATTGACATAGAAG >danRer3_refGene_NM_214784 AATAAATTATTGTACATACATTAACGTCTTACAAAATAACTACATTAAAA TTTTTTTCTAAATTTTCATCACTGAAATTATCATTTCAATCTCGTTGGTG AAAATTTCATTCAGAATCTACTTCAACAACACTGTTATATCAAACTGTTT GTGAACAAAGCGTACTCTCTTACAGATATAATACACTAATACGGTGGAGC ACCATGTGGAGAAGGCTGGTGTTGGTATCAGCACCGCCCAGCTCCTTATA CAGGCCACACTTGGGCCTGCAGTGATGACTGTCAAACCGTAAATGGACAG TCCTGCTCACTATGACCCTGCCGGACAGGGGGAGACACGCCGCTTCTCTA GGAAATCACCCCTCACTTACCCTGCCAGTGCCTAATATGGTTGAAGAATG AGGAAAAACTCCAACCGAACATACAGATATCCTCAATAGTACACATGGCG ACAAACGCGGTGAGTATATAAAGTGCCGGTGCCTGAGGCAGTTTGTGACT

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Engine behaviour: Mapping and meta-alignment Only meta-alignment

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(it might be time consuming)

Maximum accepted file size: 10 sequences (500 bps) or 1000 elements
Field separator: TAB char (\t)

MAPPING OPTIONS

Please select the collection of weight matrices to perform the mapping from nucleotides into TF binding sites (please click here for further information about the mapping functions) Matrix collections: JASPAR 1.0 TOP-50: 50 matrices

Mapping threshold quality:

0.25 0.5 0.75 1.0

Display the predictions

TF-MAP ALIGNMENT CONFIGURATION

Please select the parameters to perform the multiple TF-map alignment
(please click here for further information about the meta-alignment parameters)

0 0.1 0.25 0.5 0.75 1.0	α value
0 0.1 0.25 0.5 0.75 1.0	λ value
0 0.1 0.25 0.5 0.75 1.0	μ value
0 -1 -2 -5 -10 -20	γ value
1 10 25 50 100	c value

Show the alignment in GFF format

EXPERIMENTAL ANNOTATIONS

• Actin, α-cardiac (ACTC) gene
  
  
• See further details about the ACTC promoters HERE
  
  
• Experimental annotations included to evaluate the multiple TF-map alignment
  (extracted from ABS (Blanco et al., Nucleic Acids Research, 34:D63-D67, 2006))

ABOUT mmeta WEB SERVER

The Multiple meta-alignment ^server is the web server to mmeta, a program to align high-level sequence features taking into account their score and positional conservation. Visit the mmeta homepage for additional information about this application.

AUTHORS

Version 1 of the mmeta^server has been written by Enrique Blanco